Class Information 2021
Bio 5487
Mondays & Wednesdays, 3:00 – 4:30/5:00 (**Thursday class activities)
Room 4001B, Couch Bld or remote (Zoom link will be provided to class members)
Schedule
Topic
Presenter(s)
Readings
Presentation ppt/PDF
Monday August 30
Introduction to Course
Tim Schedl, Chris Gurnett & John Welch
Wednesday September 1
Sequencing technology
Bob Fulton
Monday September 6
Memorial Day
Wednesday September 8
Bioinformatics analysis – variant characterization I
Dustin Baldridge and Dan Wegner
Monday September 13
Bioinformatics analysis – variant characterization II
Dustin Baldridge and Dan Wegner
Wednesday September 15
Genomics of lung cancer
Sid Devarakonda
Monday September 20
Clinical translation of genetic predictors for diabetes mellitus
Fumi Urano
Wednesday September 22
Lysosomal storage disease
Patti Dickson & Mark Sands
Monday September 27
RNA targeted therapies for neurodegenerative disease
Tim Miller
Wednesday September 29
Whole exome and genome sequencing for infants with birth defects and extreme phenotype
Jennifer Wambach
Monday October 4
Variants of unknown significance and methods for high-throughput testing of variant function
Gabe Haller
Wednesday October 6
Solving the complex disorder von Willebrand disease
Jorge DiPaola
Monday October 11
TBD
Wednesday October 13
Autism genetics
Tychele N. Turner
Monday October 18
- Pharmacogenetics of lung transplantation
Laneshia Tague
Wednesday October 20
From Mila to More: Personalized therapy for rare disease
Jen Heeley
Monday October 25
From discovery to translation in cardiovascular genetics
Nate Stitziel
Wednesday October 27
Precision prevention: Using genomics to guide smoking cessation
Laura Bierut
Wednesday November 1
TBD
Wednesday November 3
Analysis of patient variants project – introduction
Yang Cao and Claire Hou
Monday November 8
Gene therapies in neuromuscular disorders
Craig Zaidman
Wednesday November 10
Analysis of patient variants project – Report of your findings
Yang Cao and Claire Hou
Monday November 15
ctDNA and MRD analysis
Aadel Chaudhuri
Wednesday November 17
Chromothripsis and other genomic rearrangements
Luis Batista
***Thursday November 18
PMP Retreat Keynote talk.
Stephanie Devaney, Chief Operating Officer of the All of Us Research Program at the National Institutes of Health
Monday November 22
Careers panel
DBBS alumni: Jarrett Glasscock (Cofactor Genomics); Nicole Renaud (Novartis); Sarah Petersen, Assistant Professor, Kenyon College; Jillian Buchan, Assistant Professor, Department of Laboratory Medicine and Pathology, University of Washington
Thanksgiving
Monday November 29
Chromoseq and clinical whole genome sequencing
Dave Spencer
Wednesday December 1
Neoantigen discovery and application
Malachi Griffith
Monday December 6
Vaccine development for brain cancers
Tanner Johanns
Wednesday December 8
Zebrafish models of human cancer
Chuck Kaufman
Note some lectures were removed as they contained unpublished materials.,
Bio 5487
Mondays & Wednesdays, 3:00 – 4:30/5:00 (**Thursday class activities)
Room 4001B, Couch Bld or remote (Zoom link will be provided to class members)
| Schedule | Topic | Presenter(s) | Readings | Presentation ppt/PDF |
| Monday August 30 | Introduction to Course | Tim Schedl, Chris Gurnett & John Welch | ||
| Wednesday September 1 | Sequencing technology | Bob Fulton | ||
| Monday September 6 | Memorial Day | |||
| Wednesday September 8 | Bioinformatics analysis – variant characterization I | Dustin Baldridge and Dan Wegner | ||
| Monday September 13 | Bioinformatics analysis – variant characterization II | Dustin Baldridge and Dan Wegner | ||
| Wednesday September 15 | Genomics of lung cancer | Sid Devarakonda | ||
| Monday September 20 | Clinical translation of genetic predictors for diabetes mellitus | Fumi Urano | ||
| Wednesday September 22 | Lysosomal storage disease | Patti Dickson & Mark Sands | ||
| Monday September 27 | RNA targeted therapies for neurodegenerative disease | Tim Miller | ||
| Wednesday September 29 | Whole exome and genome sequencing for infants with birth defects and extreme phenotype | Jennifer Wambach | ||
| Monday October 4 | Variants of unknown significance and methods for high-throughput testing of variant function | Gabe Haller | ||
| Wednesday October 6 | Solving the complex disorder von Willebrand disease | Jorge DiPaola | ||
| Monday October 11 | TBD | |||
| Wednesday October 13 | Autism genetics | Tychele N. Turner | ||
| Monday October 18 |
|
Laneshia Tague | ||
| Wednesday October 20 | From Mila to More: Personalized therapy for rare disease | Jen Heeley | ||
| Monday October 25 | From discovery to translation in cardiovascular genetics | Nate Stitziel | ||
| Wednesday October 27 | Precision prevention: Using genomics to guide smoking cessation | Laura Bierut | ||
| Wednesday November 1 | TBD | |||
| Wednesday November 3 | Analysis of patient variants project – introduction | Yang Cao and Claire Hou | ||
| Monday November 8 | Gene therapies in neuromuscular disorders | Craig Zaidman | ||
| Wednesday November 10 | Analysis of patient variants project – Report of your findings | Yang Cao and Claire Hou | ||
| Monday November 15 | ctDNA and MRD analysis | Aadel Chaudhuri | ||
| Wednesday November 17 | Chromothripsis and other genomic rearrangements | Luis Batista | ||
| ***Thursday November 18 | PMP Retreat Keynote talk. | Stephanie Devaney, Chief Operating Officer of the All of Us Research Program at the National Institutes of Health | ||
| Monday November 22 | Careers panel | DBBS alumni: Jarrett Glasscock (Cofactor Genomics); Nicole Renaud (Novartis); Sarah Petersen, Assistant Professor, Kenyon College; Jillian Buchan, Assistant Professor, Department of Laboratory Medicine and Pathology, University of Washington | ||
| Thanksgiving | ||||
| Monday November 29 | Chromoseq and clinical whole genome sequencing | Dave Spencer | ||
| Wednesday December 1 | Neoantigen discovery and application | Malachi Griffith | ||
| Monday December 6 | Vaccine development for brain cancers | Tanner Johanns | ||
| Wednesday December 8 | Zebrafish models of human cancer | Chuck Kaufman | ||
| Note some lectures were removed as they contained unpublished materials., | ||||